Supervisors: Russ Brown (rhb37@), Paul Grant (pg384@), Orr Yarkoni (oy210@)
Timing: Michaelmas term
Prerequisites: This is an introductory course that assumes no prior knowledge of biology beyond GCSE level. Students who haven't taken GCSE biology or equivalent should be able to manage the course too, but may like to talk to the course organisers first.
Structure: 16 lectures, 1 laboratory class
This is an intensive introductory level undergraduate course targeted at third year Engineering students. This course will be delivered through lectures and a laboratory class.
On completion of the course, students will:
The lecture material will be solely assessed by a written examination (1.5 hours) at the start of the Easter term and coursework derived from the laboratory classes.
|Full Technical Report (Genetic regulatory systems)|
No FTR for 3G1 will be offered this year.
This course will provide a basic grounding in key aspects of molecular bioscience with an emphasis on bioscience engineering.
This course will introduce those elements of molecular biology that are relevant to further study in bioscience and engineering applications.
|1-3||Overview/introduction-why engineer living systems? Life: cells to organisms|
|4-5||Central dogma of molecular biology; Gene regulation|
|6-7||Genetic engineering I: basic parts, methods and terminology|
|8-9||Genetic Engineering II: Further methods, case studies|
|10-12||Metabolic Engineering: Cellular metabolism; catabolism/anabolism, Core molecular types; Metabolic engineering principles and case studies|
|13-15||Genomics: Genome sequencing/annotation/key computational methods; Functional studies: Gene expression/regulatory networks/perturbation studies|
|Supervisions:||supervision groups will be assigned once course numbers are finalised.|
|Lab||Fri 25th October; Teaching Lab, Department of Plant Sciences; will take 11am - 6pm with lunch break, shorter if you are organised|
|Lab||Fri 1st November; Teaching Lab, Department of Plant Sciences; will take 11am - 6pm with lunch break, shorter if you are organised|
|Lecture pdf files: N.B. Lectures are for your own use and should not be distributed/made public.|
|Lecture 8 Extra Notes|
|Examples paper 1||Lectures 1-9|
|Examples paper 1 crib||Lectures 1-9|
|Examples paper 2||Lectures 10-12|
|Examples paper 2 crib||Lectures 10-12|
|Examples paper 3||Lectures 13-16|
|Examples paper 3 crib||Lectures 13-16|
|Supervision questions/cribs||Previous years|
|Examples paper 1||2011|
|Examples paper 1 crib||2011|
|Examples paper 2||2011|
|Examples paper 2 crib||2011|
|Examples paper 3||2011|
|Examples paper 3 crib||2011|
|Mock exam and Crib|
|3G1 Mock Exam|
|3G1 Mock Exam Crib|
|3G1 2010-2011 Exam|
|3G1 2010-2011 Crib|
General text (should be in libraries): Introduction to Genetic Analysis (10th Ed.) Griffiths, Wessler, Carroll and Doebley Publisher: Freeman ISBN13: 978-1-4292-7634-4
The following should be available through college libraries but are also available in full for searching online via NCBI bookshelf: